Quality management software (QMS) has become an essential part of conducting important business actions in multiple industries. As the technology has evolved over the years, QMS software has only become more efficient and has ended up being essential to the success of large companies.
Looking to grow your business? You should try using QMS systems to centralize all quality control measures and ensure compliance with your company’s standards. Read more to know about the best quality control software in the market that you can use right now.
Quality management software is a special system designed to help organizations streamline, manage, and optimize their products and services. This software helps establish a productive process that increases the quality and quantity of the company’s output.
QMS acts as the backbone of many operations and helps meet significant benchmarks for optimal business results. Adopting quality management software helps businesses set high-quality standards for their employees and also helps them achieve their goals by improving the company’s end product.
In essence, quality control software is proprietary software (meaning: closed-source program) specially designed to provide critical tools that every organization should adapt to thrive in today’s competitive business environment.
To help your agency find the best quality management system software, we have done the research and provided a list of the best QMS software below.
ETQ Reliance is one of the leading quality management control software solutions that you can find in 2025. Led by its cloud-native SaaS structure, ETQ is an adaptable platform that can easily be mastered.
This software offers multiple applications for document control, training management, audit management, supplier quality management, advanced analytics, risk assessment, and more. With ETQ by your side, you can enhance compliance and improve your company’s efficiency.
ETQ Reliance Price: $25,000 Per Year
Playvox offers AI-infused solutions to businesses in managing their production, communication, and all-important interactions. Putting strong emphasis on quality control, Playvox aims to improve productivity to drive better results for its clients.
It specializes in the customer service part of businesses and helps them in leaving a strong impression on their customers. With Playvox, you can provide a better customer experience and also increase your performance through its tools.
The software provides multiple management tools that will help you manage the workflow and also keep an eye on day-to-day activities.
Playvox Price: $47,840 per year
MasterControl is created to help organizations in regulated industries streamline and automate important quality processes. This software offers a comprehensive set of tools for quality control in various aspects of business.
You can use MasterControl to create, assign, and track training programs to ensure compliance with regulatory standards set in your company. It also facilitates change control, audit management, and customer complaint handling at a higher level.
While MasterControl helps you increase efficiency in your agency, it also helps you manage risks and makes it possible to investigate and mitigate quality issues proactively. It has a great track record of ensuring quality management is done the right way in all types of firms.
The software clearly ensures that organizations can maintain high product quality and perfectly comply with their regulations. Its user-friendly interface and powerful reporting tools further cement its position as one of the best quality management systems in 2025, making it a valuable asset for any company.
MasterControl Price: $25,000 Per Year
ComplianceQuest is a cloud-based quality management system created on a special platform that you can use to connect your staff and achieve the exceptional. It offers a wide range of features tailored to meet the needs of various industries and help them stay true to their regulatory requirements.
A major highlight of ComplianceQuest is its robust document management capabilities, which you can use to ensure that all important documents are recorded, up-to-date, and easily accessible to all members of the staff. The software also has features like version control and electronic signatures.
ComplianceQuest also has tools for audit management and features for planning, executing important changes in the agency. Additionally, the software also boasts strong capabilities for managing corrective and preventive actions (CAPA) in organizations.
All these features make ComplianceQuest a great option for companies to ensure proper quality control and management.
ComplianceQuest Price: $360 Per Year
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Qualio is the best quality management system for science-based companies. If you run a scientific organization, you should go for Qualio to establish proper quality control in your company.
A cloud-based software, Qualio helps science organizations streamline and automate their quality processes according to their goals and regulations. Suited for companies in the pharmaceutical, biotechnology, and medical fields, where compliance with regulatory standards is critical.
It presents superior data handling features to ensure each bit of data is recorded and arranged the right way. Its cloud-based nature ensures that it is flexible, easy to understand/use, and accessible from anywhere, making it an ideal solution for modern science firms.
Qualio Price: $12,000 Per Year
HSI Donesafe is a comprehensive quality management software designed to enhance workplace safety and quality compliance. A global leader in safety management across multiple industries, HSI Donesafe offers quality management tools with the aim of supporting a positive health and safety environment.
With HSI Donesafe by your side, you can achieve great results that were not possible before. The platform also makes it easy to get deeper insights into important agency data. HSI Donesafe achieves this by eliminating multiple-point solutions, data silos and many more processes. The software also has numerous safety management modules to protect its clients.
HSI Donesafe is adept at handling data; it can also unify all data and provide unique insights to help you understand it. Additionally, the platform can also integrate with other third-party systems like HR workforce management, CRM software, and many more to completely integrate into an organization’s structure.
Overall, HSI Donesafe is a versatile solution for companies looking for effective quality management systems and to enhance their management processes.
HSI Donesafe Price: $5,000 Per Year
Arena QMS is a top-rated QMS software designed to help companies interconnect and ensure quality management processes for increased productivity. Arena QMS is best for companies in highly regulated industries that produce medical devices, electronics, and even aerospace.
With Arena QMS, you can connect your quality records directly to the product design in a single system and make important documents way more accessible. The software works to simplify compliance within the company and also reduces the audit risk significantly.
It creates a single system of quality management and connects each important task in the company to it to guarantee quality management. Using this technology, Arena QMS also helps in speeding up the resolution of issues.
The product-centric approach helps Arena QMS in integrating quality management throughout the company and establishing a single source of reference from which all data can be accessed.
It offers better collaboration, scalability, flexibility, enhanced compliance, and improved efficiency, making Arena QMS the right option as one of the best quality management systems.
Arena QMS Price: $2,268 Per Year
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Greenlight Guru is the best quality management system for the medical device industry. It specializes in companies that sell medical devices and help them manage quality and compliance throughout the production process.
The industry-specific design allows Greenlight Guru to fully cater to the medical industry and be the solution they need to efficiently run their operations. Established in 2013, Greenlight Guru has now established itself as an industry leader with its cloud-based solutions.
The platform offers a comprehensive set of tools to ensure proper quality management and manage critical operations, including product development and the production process. It also has clinical data management tools to capture all important data and manage it in a single system.
Greenlight Guru stands out as a specialized QMS software that offers user-friendly collaborative features. Its industry-specific design makes it an invaluable asset for companies in the medical field and helps in reducing risks and bringing high-quality medical devices to market more efficiently.
Greenlight Guru Price: $25,000 Per Year
Ideagen is a global software company specializing in quality management systems. Its core mission is to help companies reach regulatory compliance, reduce numerous risks, and increase efficiency in day-to-day operations.
It offers a centralized and integrated platform that breaks down communication barriers and ensures quality management. Ideagen’s product is designed to streamline all quality-related processes and aims to solve all problems.
Offering features like document control, corrective and preventive actions (CAPA), audit management, training management, risk management, and also has user-friendly integration capabilities.
This one is a robust quality management software with deep industry expertise in highly regulated sectors. It’s commitment towards providing solutions to address the complex market needs.
Ideagen Price: $25,000 Per Year
AlisQi is a specialized quality management system that puts strong emphasis on the manufacturing industries. AlisQi aims to provide a simple and elegant solution to complex company problems related to manufacturing and quality of the products.
The software doesn’t require extensive IT knowledge and can easily be learned by anyone in the organization. AlisQi offers numerous quality control features like data collection, a built-in SPC toolbox, calibration management and much more.
AlisQi also has a real-time dashboard for reporting and handling data, and the platform is also accessible by mobile. In essence, AlisQi differentiates itself by offering a powerful quality control system that can fix any mistake and shape even the biggest companies into manufacturing leaders.
AlisQi Price: $21,000 Per Year
The search for the best quality management software is bound to put you in front of software that claims to be the best in the industry, and the truth is that they are all the best in what they do. To find the best platform, you need to first figure out what you need for your company, and then find the software that is created to help your company.
Ultimately, the best QMS software is the one that matches your goals and can correct the wrongs of your employees. By carefully evaluating your requirements and the trends in the market, you can get the right QMS software for you and find the innovative solution your company requires.
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Ans: A quality management software is used to establish proper quality control in companies worldwide. Companies like ETQ Reliance, MasterControl, and AlisQI are some of the best QMS software providers in the world.
Ans: It is hard to determine the best QMS software as all software cater to different industry types. To find the best QMS software, you should search according to your needs and goals.
Ans: The 5 core tools of QMS are APQP (Advanced Product Quality Planning, PPAP (Production Part Approval Process), FMEA (Failure Mode and Effects Analysis), MSA (Measurement Systems Analysis), and SPC (Statistical Process Control).
Ans: MasterControl is one of the most used QMS software in the world as it cater to a wide range of companies.
Ans: Documentation, quality control, and quality management are the three main categories of QMS.
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